(BY-ahp-see): A procedure used to remove cells or tissues to look at them under a microscope and check for signs of disease. When an entire tumor or lesion is removed, the procedure is called an excisional biopsy. When only a sample of tissue is removed, the procedure is called an incisional biopsy or core biopsy. When a sample of tissue or fluid is removed with a needle, the procedure is called a needle biopsy or fine-needle aspiration.

: A term for diseases in which abnormal cells divide without control. Cancer cells can invade nearby tissues and can spread through the bloodstream and lymphatic system to other parts of the body.

(kar-sin-O-ma): Cancer that begins in the skin or in tissues that line or cover internal organs.

(kee-mo-THER-a-pee): Treatment with anticancer drugs.

: A research study that tests how well new medical treatments or other interventions work in people. Each study is designed to test new methods of screening, prevention, diagnosis, or treatment of a disease.

(KRYE-o-SIR-jer-ee): Treatment performed with an instrument that freezes and destroys abnormal tissues. This procedure is a form of cryotherapy.